Day: 14 January 2016

Be careful with your antibodies

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Source: Nature.com and Human Protein Atlas

Antibodies against common cellular targets (e.g. ubiquitin) are available from many different commercial sources. But are they all created equally? And are they appropriately validated to demonstrate specificity? This is important, because poorly characterised antibodies can yield unreliable results, and non-reproducibility between different labs. Read more